3,502 research outputs found

    The stress system generated by an electromagnetic field in a suspension of drops

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    The stress generated in a suspension of drops in the presence of a uniform electric field and a pure straining motion, taking into account that the magnetohydrodynamic effects are dominant was calculated. It was found that the stress generated in the suspension depended on the direction of the applied electric field, the dielectric constants, the vicosity coefficients, the conductivities, and the permeabilities of fluids inside and outside the drops. The expression of the particle stress shows that for fluids which are good conductors and poor dielectrics, especially for larger drops, magnetohydrodynamic effects end to reduce the dependence on the direction of the applied electric field

    vaccination in a patient with Behcet's disease

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    Case report: A 25-year-old man with Behcet's disease was admitted because of weakness of the lower limbs and difficulty in urination. He had received a rabies vaccination 2 months previous because he had been bitten by a dog.Findings: Clinical and laboratory findings supported acute transverse myelitis. A hyperintense lesion and expansion at the level of conus medullaris was detected on spinal magnetic resonance imaging.Conclusion: Although neurologic involvement is one of the main causes of mortality and morbidity in Behcet's disease, the factors that aggravate the involvement of the nervous system are still unclear. Vaccination may have been the factor that had activated autoimmune mechanisms in this case. To our knowledge, involvement of the conus medullaris in Behcet's disease after rabies vaccination has not been reported

    On The Dynamics Of The Difference Equation

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    In this paper, we studied the global behavior of the difference equation nbspwith non-negative parameters and the initial conditions nbspare non-negative real numbers

    Scrutinising the exceptionalism of young rural NEETs: A bibliometric review

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    The situation of rural NEETs aged 15 to 24 remains understudied. However, transitions from adolescence to emerging adulthood are very demanding for those in the countryside. Our paper discusses this gap by characterising the scholarship focusing on rural NEETs. We undertook a bibliometric review based on 325 entries on Web of Science (WoS) using the Bibliometrix analysis package. Our approach included descriptive bibliometric analysis, co-citation networks assessment, and thematic analysis. Our findings show that the investigation efforts depicting younger rural NEET are recent and marginal in the larger context of international NEETs scholarship. The field is dominated by economy- and sociology-led networks. Concerns regarding health and employment issues are central in international publishing trends, showing a dominant youth-at-risk approach to this group. Still, themes associated with adolescent NEETs and relevant programs’ assessment are gaining traction. Our findings show a need for funding research initiatives to reduce the invisibility of young rural NEETs.info:eu-repo/semantics/acceptedVersio

    Computational Biology in Acute Myeloid Leukemia with CEBPA Abnormalities

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    __Abstract__ In the last decade, tiling-array and next-generation sequencing technologies allowed quantitative measurements of different cellular processes, such as mRNA expression, genomic changes including deletions or amplifications, DNA-methylation, chromatin modifications or Protein-DNA-binding interactions. Using these technologies, thousands of features can now be measured simultaneously in a patient cell sample. The use of for instance mRNA expression profiles or DNA-methylation profiles have already provided new insight into the molecular biology of patients with Acute Myeloid Leukemia (AML). AML is a blood cell malignancy, in which primitive myeloid cells have been transformed and accumulate in the bone marrow and blood. Different forms of AML exist with different molecular abnormalities that associate with distinct responses to therapy. Many subgroups with comparable mRNA expression or DNA-methylation patterns were identified. These studies also revealed the existence of novel previously undefined AML subtypes. Among those was a group of patients with a mutation in a gene called CEBPA. CEBPA is a gene that encodes the transcription factor CCAAT Enhancer Binding Protein Alpha (C/EBPα), which controls the expression of genes in myeloid progenitor cells. Mutated CEBPA encodes a dysfunctional C/EBPα-protein, which consequently results in aberrant control of “target genes”. In this thesis we focus particularly on the role of CEBPA. We studied the predictive and prognostic relevance of mutated CEBPA, and analyzed in a genome wide fashion the mRNA expression, DNA-methylation and the protein-DNA-binding levels corresponding to (mutated) CEBPA in AML. For the analysis of protein-DNA-binding, we developed a novel statistical methodology. With this statistical methodology we studied the fundamental role of (mutant) C/EBPα binding and the effect on gene expression levels. We also integrated gene expression with DNA-methylation profiles of hundreds of AML patients and revealed the existence of two previously unidentified AML subtypes

    Health, Financial Incentives and Retirement in Spain

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    We estimate the impact of health and financial incentives on the retirement transitions of older workers in Spain. Individual measures of pension wealth, peak and accrual values are constructed using labor market histories and health shocks are derived as changes in a composite health stock measure over time. We examine labour market exits into both old age retirement and a broader definition of retirement including inactivity, while controlling for unobserved heterogeneity. We find that pension wealth, accrual and peak value are significant determinants of retirement decisions, although their effect is weaker in the case of the broad definition of retirement. Initial health stock shows a significant impact on both definitions of retirement. Only large negative health shocks have a significant effect on the probability of entering the broader definition of retirement. Unlike previous literature, we find that (i) financial incentives, when measured adequately, exert a greater impact on retirement behaviour than health shocks, and (ii) initial health stock plays a more important role than health shocks in determining retirement decisions. We also perform simulations of a recently enacted reform of pension incentives and show how its expected effects compare to those of health improvements

    On the Error Probability of Cognitive RF-FSO Relay Networks over Rayleigh/EW Fading Channels with Primary-Secondary Interference

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    Free space optical (FSO) communication has emerged to provide line of sight connectivity and higher throughput over unlicensed optical spectrums. Cognitive radio (CR), on the other hand, can utilize the radio frequency (RF) spectrum and allow a secondary user (SU) to share the same spectrum with the primary user (PU) as long as the SU does not impose interference on the PU. Owing to the potential of these emerging technologies, to provide full spectrum efficiency, this paper focuses on the mixed CR RF-FSO transmission scheme, where RF communication is employed at one hop followed by the FSO transmission on the other hop in a dual-hop decode-and-forward (DF) configuration. To quantify the performance of the propose

    Self-defined information indices: application to the case of university rankings

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    [EN] University rankings are now relevant decision-making tools for both institutional and private purposes in the management of higher education and research. However, they are often computed only for a small set of institutions using some sophisticated parameters. In this paper we present a new and simple algorithm to calculate an approximation of these indices using some standard bibliometric variables, such as the number of citations from the scientific output of universities and the number of articles per quartile. To show our technique, some results for the ARWU index are presented. From a technical point of view, our technique, which follows a standard machine learning scheme, is based on the interpolation of two classical extrapolation formulas for Lipschitz functions defined in metric spaces-the so-called McShane and Whitney formulae-. In the model, the elements of the metric space are the universities, the distances are measured using some data that can be extracted from the Incites database, and the Lipschitz function is the ARWU index.The third and fourth authors gratefully acknowledge the support of the Ministerio de Ciencia, Innovacion y Universidades (Spain), Agencia Estatal de Investigacion, and FEDER, under Grant MTM2016-77054-C2-1-P. The first author gratefully acknowledge the support of Catedra de Transparencia y Gestion de Datos, Universitat Politecnica de Valencia y Generalitat Valenciana, Spain.Ferrer Sapena, A.; Erdogan, E.; JimĂ©nez-FernĂĄndez, E.; SĂĄnchez PĂ©rez, EA.; Peset Mancebo, MF. (2020). Self-defined information indices: application to the case of university rankings. Scientometrics. 124(3):2443-2456. https://doi.org/10.1007/s11192-020-03575-6S244324561243Aguillo, I., Bar-Ilan, J., Levene, M., & Ortega, J. (2010). Comparing university rankings. 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Generating new indicators on universities by linking data in open platforms. Journal of the Association for Information Science and Technology, 68(2), 508–529.CobzaƟ, ƞ., Miculescu, R., & Nicolae, A. (2019). Lipschitz functions. Berlin: Springer.Deza, M. M., & Deza, E. (2009). Encyclopedia of distances. Berlin: Springer.2019 U-Multirank ranking: European universities performing well. https://ec.europa.eu/education/news/u-multirank-publishes-sixth-edition-en .Dobrota, M., Bulajic, M., Bornmann, L., & Jeremic, V. (2016). A new approach to the QS university ranking using the composite I-distance indicator: Uncertainty and sensitivity analyses. Journal of the Association for Information Science and Technology, 67(1), 200–211.Falciani, H., Calabuig, J. M., & SĂĄnchez PĂ©rez, E. A. (2020). Dreaming machine learning: Lipschitz extensions for reinforcement learning on financial markets. Neurocomputing, 398, 172–184.Kehm, B. M. (2014). Global university rankings—Impacts and unintended side effects. European Journal of Education, 49(1), 102–112.Lim, M. A., & Øerberg, J. W. (2017). Active instruments: On the use of university rankings in developing national systems of higher education. Policy Reviews in Higher Education, 1(1), 91–108.Luo, F., Sun, A., Erdt, M., Raamkumar, A. S., & Theng, Y. L. (2018). Exploring prestigious citations sourced from top universities in bibliometrics and altmetrics: A case study in the computer science discipline. Scientometrics, 114(1), 1–17.Marginson, S. (2014). University rankings and social science. European Journal of Education, 49(1), 45–59.Pagell, R. A. (2014). Bibliometrics and university research rankings demystified for librarians. Library and information sciences (pp. 137–160). Berlin: Springer.Rao, A. (2015). Algorithms for Lipschitz extensions on graphs. Yale University: ProQuest Dissertations Publishing, 10010433.Rosa, K. D., Metsis, V., & Athitsos, V. (2012). Boosted ranking models: A unifying framework for ranking predictions. Knowledge and Information Systems, 30(3), 543–568.Saisana, M., d’Hombres, B., & Saltelli, A. (2011). Rickety numbers: Volatility of university rankings and policy implications. Research Policy, 40(1), 165–177.Tabassum, A., Hasan, M., Ahmed, S., Tasmin, R., Abdullah, D. M., & Musharrat, T. (2017). University ranking prediction system by analyzing influential global performance indicators. In 2017 9th International Conference on Knowledge and Smart Technology (KST) (pp. 126–131) IEEE.Van Raan, A. F. J., Van Leeuwen, T. N., & Visser, M. S. (2011). Severe language effect in university rankings: Particularly Germany and France are wronged in citation-based rankings. Scientometrics, 88(2), 495–498.von Luxburg, U., & Bousquet, O. (2004). Distance-based classification with Lipschitz functions. Journal of Machine Learning Research, 5, 669–695
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